Visual outcomes of non-diffractive extended-depth-of-focus and enhanced monofocal intraocular lenses: A case-control study.

OBJECTIVE: To compare the visual outcomes of a non-diffractive extended-depth-of-focus (EDoF) intraocular lens (IOL) with an enhanced monofocal IOL. METHODS: We evaluated 76 eyes from 38 patients who had undergone bilateral cataract surgery with implantation of either an EDoF IOL (AcrySof IQ Vivity, n = 40 eyes) or an enhanced monofocal IOL (Tecnis Eyhance, n = 36 eyes). Objective refraction, monocular and binocular uncorrected and corrected distance visual acuity (UDVA, CDVA), uncorrected and distance-corrected intermediate visual acuity (UIVA, DCIVA), uncorrected and distance-corrected near visual acuity (UNVA, DCNVA), binocular defocus curves, contrast sensitivity, halo and glare perception, and spectacle independence were compared. RESULTS: Monocular and binocular UDVA, CDVA, UIVA, and DCIVA were comparable in both groups, whereas UNVA and DCNVA were significantly better with the Vivity group than with the Eyhance group. The two groups had no statistically significant difference regarding photopic and scotopic contrast sensitivities or halo and glare perception. Compared to the Eyhance IOL, the Vivity IOL had a larger landing zone in the defocus curve and provided higher spectacle independence for near vision. CONCLUSION: Both the AcrySof IQ Vivity and Tecnis Eyhance IOLs had excellent distant and intermediate visual acuity, while the former had more satisfactory near vision outcomes with greater spectacle independence rate. No differences were obtained between two IOLs in terms of patient satisfaction and visual disturbances such as halo and glare.

Flanged iris hook for capsular bag stabilization.

A new surgical technique was demonstrated for fixating the capsular bag to the sclera using a capsular tension segment (CTS) and a flanged iris hook. In a patient with a 180-degree zonular dialysis, a capsular tension ring was implanted into the capsular bag, and a CTS was placed into the zonular dialysis area after cataract removal. Then, an iris hook was directed to the anterior chamber through a side port opposite the zonular dialysis area. After the hook tip was placed into the eyelet of the CTS, a 30-gauge injector was used to guide the hook tip out. Tension was adjusted to ensure the capsular centralization, and a flange was created using cautery. Finally, the procedure was completed by embedding the flange into the sclera. This method is simple, minimally invasive, and time-saving by eliminating the scleral suturing, scleral flaps, or large conjunctival dissections.

The efficacy and safety profile of cataract procedures performed with a sensor-embedded handpiece and a new hybrid phaco tip.

OBJECTIVE: To evaluate the efficacy and safety of the new Intrepid Hybrid tip and Active Sentry handpiece in comparison to the Intrepid Balanced tip and Centurion Ozil handpiece. METHODS: One hundred sixty-eight eyes were included in the study and randomized into Group 1 (Active Sentry handpiece + Intrepid Hybrid tip, n = 86) and Group 2 (Centurion Ozil handpiece + Intrepid Balanced tip, n = 82). Data were collected from the phaco device, including total U/S time, cumulative dissipated energy (CDE), the total number of active surge mitigation actuations (ASM actuations), torsional amplitude, torsional amplitude on time, estimated fluid of aspirated, and aspiration time. Endothelial cell count (ECC) and central corneal thickness (CCT) were assessed. A correlation analysis was performed between ASM actuations, phaco metrics, and patient characteristics in Group 1. RESULTS: The CDE, torsional amplitude measured in Group 1 (8.8 ± 3.9, 51.2 ± 13.3, respectively) were significantly lower than those of Group 2 (10.4 ± 4.2, 65.2 ± 9.3, respectively). While no complications were observed in group 1, there were posterior capsule rupture in 2 eyes and iris damage in 1 eye in group 2. The mean ECC and CCT were similar at 1 month. The ASM actuations were more engaged in the eyes with pseudoexfoliation and small pupils. CONCLUSION: The combination of the new Intrepid Hybrid tip and Active Sentry handpiece enables safer cataract procedures without compromising efficacy due to its surge prevention mechanisms and special tip design. It could be a good option for residents in training.

Results of a novel surgical technique for iridodialysis repair using an iris retractor segment.

PURPOSE: To describe a novel surgical technique for iridodialysis repair using an iris retractor segment and report its clinical results. METHODS: Fifty-three eyes of 53 patients who underwent iridodialysis repair using an iris retractor segment were enrolled in this retrospective study. Data recorded from patient files consisted of age, sex, degree of iridodialysis, surgical techniques, number of segments used, preoperative and postoperative corrected distance visual acuity (CDVA), intraocular pressure (IOP), complications, and follow-up time. RESULTS: Mean follow-up time was 34.4 months. The subjects included 29 men (54.7%) and 26 women (45.3%), and the mean age was 56.6 ± 14.0 years. According to the degree of iridodialysis, the patients were divided into Group 1 (60°-89°, n = 19) and Group 2 (90°-270°, n = 34). During the iridodialysis repair for Group 1, a single segment was sufficient; however, in Group 2, one segment was used in 18 eyes (52.9%), two segments in 15 eyes (44.1%), and three segments in one eye (2.9%). The pre- and postoperative last control CDVA value in Group 2 was significantly lower than in Group 1. The pre- and postoperative IOPs for Group 2 were significantly higher than Group 1. CONCLUSION: Iridodialysis repair using an iris retractor segment is a minimally invasive technique and found to be safe and effective. It will be a good option for patients with large iridodialysis, as it avoids excessive surgical manipulations and prolonged surgical time.

Acute effect of pseudoephedrine on macular microcirculation in healthy subjects: an optical coherence tomography angiography study.

PURPOSE: To quantitatively evaluate the acute effects of pseudoephedrine on the macular microvasculature using optical coherence tomography angiography (OCTA). STUDY DESIGN: Randomized placebo-controlled clinical study. METHODS: In this study, 60 right eyes of 60 healthy subjects were divided into 2 groups. The study group received 60 mg of pseudoephedrine and the control group received a placebo. All participants underwent OCTA at baseline and 1 h after oral intake. Superficial macular flow area, foveal avascular zone (FAZ), superficial macular vessel density, central foveal thickness (CFT) and subfoveal choroidal thickness (SFCT) were analyzed. RESULTS: Baseline superficial macular flow area, FAZ area, superficial macular vessel density, CFT and SFCT measurements in the study and control groups showed no significant difference (p > 0.05 for all). Oral pseudoephedrine intake caused a significant reduction in superficial macular flow area, FAZ area, superficial macular vessel density and SFCT measurements when compared with baseline (p < 0.05 for all). However, there was no significant difference in CFT after oral pseudoephedrine intake (p > 0.05). CONCLUSION: Oral pseudoephedrine intake causes a significant decrease in superficial macular blood flow and SFCT. Impairmant of macular microcirculation can be detected noninvasively and quantitavitely by OCTA.

Outcomes of a new suture technique for the treatment of dislocated intraocular lenses: locked loop on the haptic.

PURPOSE: To evaluate surgical and refractive outcomes of a new sutured scleral fixation technique in the management of subluxated intraocular lenses (IOLs). METHODS: Nineteen eyes treated with the new scleral fixation technique were included. The mean corrected distance visual acuity (CDVA), postoperative refraction error, mean endothelial cell count (ECC), and complications were recorded. All patients were evaluated immediately postoperatively, at 1 and 7 days, and then at 1, 3, and 6 months. RESULTS: The mean duration of follow-up of the patients was 10 months (range, 6-15 months). The mean CDVA was 0.41 ± 0.1 logMAR (logarithm of minimum angle of resolution) preoperatively and was 0.08 ± 0.07 logMAR postoperatively. The mean astigmatism was - 2.22 ± 1.86 D preoperative and was - 0.86 ± 0.58 D postoperative. The mean preoperative and postoperative ECC was 2455 ± 288 and 2352 ± 288, respectively. One patient (5.26%) experienced vitreous hemorrhage, and two (10.52%) experienced intraocular pressure elevation. IOL tilt and decentralization, conjunctival erosion, and cystoid macular edema were not observed in any eyes during follow-up. CONCLUSION: This new IOL repositioning technique can be applied in a short surgical time and provides a stable IOL centration on long-term follow-up.

New Scleral Fixation Technique for Subluxated Posterior Chamber Intraocular Lens.

OBJECTIVES: This study describes a new scleral fixation technique to treat a subluxated intraocular lens (IOL). METHODS: Four eyes of 4 patients were treated for a subluxated IOL with the described technique at Batigoz Eye Hospital. Demographic data, IOL type, and follow-up details were recorded, including the length of follow-up, postoperative refraction error, and complications. RESULTS: The study included 2 female and 2 male patients. The median age was 54 years (range: 45-66 years). The mean duration of follow-up was 8 months (range: 5-13 months). Two of the subluxated IOLs were a monoblock subluxation of the IOL and the capsular tension ring, 2 were a 3-piece IOL. Follow-up examinations revealed no astigmatism >1.50 D. An anterior vitrectomy was performed in 1 patient who had preoperatively prolapsed vitreous in the anterior chamber. No complication was observed throughout the follow-up. CONCLUSION: This new scleral fixation technique facilitates fixation of a dislocated IOL. Compared with previous methods, this technique provides fixation of the subluxated IOL to the sclera with a less invasive procedure and less intraocular manipulation.

Comparison of new monofocal innovative and standard monofocal intraocular lens after phacoemulsification.

PURPOSE: To evaluate the early findings of new monofocal intraocular lens (Tecnis® Eyhance) in comparison with standard monofocal intraocular lens (Tecnis® 1-piece) in patients who underwent cataract surgery. METHODS: Sixty-four eyes of thirty-two patients (each intraocular lens model was implanted bilaterally in 16 patients) were included in this retrospective study. Preoperative and postoperative (at one month) manifest refraction, spherical equivalent (SE) values, monocular and binocular uncorrected distance visual acuity (UDVA), corrected distance visual acuity (CDVA), uncorrected intermediate visual acuity (UCIVA), distance-corrected intermediate visual acuity (DCIVA), distance-corrected near visual acuity (DCNVA), binocular defocus curve, photopic contrast-sensitivity, spectacle independence, photic phenomena, tolerance to residual refractive errors and complications were recorded. RESULTS: The mean monocular postoperative UDVA, CDVA, DCNVA, spherical equivalent and cylinder values were comparable between each group (p > 0.05). Monocular and binocular DCIVA and UCIVA were significantly higher in Tecnis® Eyhance group than Tecnis® 1-piece group (p = 0.033, p = 0.038, respectively). No statistically significant difference was detected between groups regarding the photopic contrast sensitivities for any spatial frequency (p > 0.05). Spectacle independence was significantly higher in Tecnis® Eyhance group than Tecnis® 1-piece group. Tecnis® Eyhance IOL revealed a good tolerance to unexpected residual refractive errors than Tecnis® 1-piece IOL. CONCLUSION: Tecnis® Eyhance appears to be an effective option for both patients and surgeons regarding better intermediate visual acuities and more forgiving for residual refractive errors relative to the standard monofocal intraocular lenses. However, longer follow-up studies with larger group of patients are needed to evaluate the effectiveness of Tecnis® Eyhance intraocular lens.

The influence of selective laser trabeculoplasty on the success of trabeculectomy.

PURPOSE: The purpose of this to investigate whether selective laser trabeculoplasty (SLT) has any effect on the success of trabeculectomy. PATIENTS AND METHODS: Thirteen-one eyes of 29 primary open-angle glaucoma patients who underwent SLT before trabeculectomy and 29 eyes of 27 patients with the same inclusion criteria which underwent trabeculectomy without prior SLT in the Sifa University and in the Batigöz Eye Hospital in January 2012 and November 2012 were reviewed. All patients underwent trabeculectomy for uncontrolled open-angle glaucoma with the same technique. The results were evaluated 3, 6, 12, 18, and 24 months later after surgery. The statistical analysis was performed with the Mann-Whitney U-test. Fisher's Exact Chi-square test was used to compare the continuous and categorical variables. RESULTS: The mean intraocular pressure (IOP) before surgery was 24.1 ± 1.9 in the SLT-performed group and 26.7 ± 1.6 in the non-SLT-performed group. Twenty-four months later, the mean IOP was 15.1 ± 1.2 in the SLT-performed group and 15.4 ± 1.4 in the non-SLT performed group. There was no difference in the IOP drop after trabeculectomy between the two groups (P = 0.531). CONCLUSIONS: SLT has no influence on trabeculectomy success.

Evaluation of the effect of daily activities on intraocular pressure in healthy people: is the 20 mmHg border safe?

PURPOSE: The aim of this prospective study was to evaluate the intraocular pressure (IOP) variations during daily activities such as reading, speaking and carrying in regard to investigating whether an elevation or decrease exists. SUBJECTS AND METHODS: Forty-four eyes of 44 healthy subjects were evaluated. The IOP was measured in relaxation and after reading, speaking and carrying a shopping bag for 5 min on different days, respectively. The subjects rested for 15 min between the activities. Mean initial IOP levels were compared with mean IOP levels after reading, speaking and carrying a shopping bag with paired t test. A p value of 0.05 was considered as statistically significant. RESULTS: We observed no changes in mean IOP after reading (p = 0.188). Mean IOP was increased after speaking and carrying compared with mean basic IOP (p = 0.001 and p = 0.001, very significant, respectively). The mean IOP began to decrease 15 min after speaking and carrying and came back to the baseline values one hour later. CONCLUSIONS: The IOP is not stable during daily activities. Simple actions such as carrying or speaking have an increasing effect on IOP. This should be taken into consideration in glaucoma patients during control measurements, especially in patients in whom the IOP was near to the 20 mmHg border.

Intraocular lens implantation without the use of ophthalmic viscosurgical device.

The purpose of this study was to determine whether single-piece hydrophilic acrylic intraocular lens can be safely implanted without the use of ophthalmic viscosurgical devices. This retrospective study comprised 100 eyes having phacoemulsification and intraocular lens implantation without the use of ophthalmic viscosurgical device. 80 eyes with the use of a viscosurgical device are used as control group. In this intraocular lens implantation technique, the anterior chamber was maintained with an irrigation cannula and intraocular lens was implanted with a lens injector. Visual acuity, corneal clarity and edema, intraocular pressure, and corneal endothelial cell count were evaluated preoperatively and postoperatively at days 1, 7, and 30. Corneal endothelial cell count was repeated 2 weeks after surgery. Complications of this technique were also evaluated. No significant complications of this intraocular lens implantation technique, such as posterior capsule rupture, intraocular lens buttonholing, zonular dialysis, Descemet's tear/detachment, occurred. On the seventh postoperative day, 90 % of eyes achieved 20/20 or better vision. There was no difference in corneal endothelial cell loss between viscoelastic device-used and not-used cases (p = 0.356). When implanting intraocular lens without the use of ophthalmic viscosurgical device, significant intraoperative complications did not occur. The possible advantages are shortened surgery time, avoidance of postoperative IOP spike from ocular viscosurgical device (OVD) remnant, and reduced cost.

Evaluation of Different Power of Near Addition in Two Different Multifocal Intraocular Lenses.

Purpose. To compare near, intermediate, and distance vision and quality of vision, when refractive rotational multifocal intraocular lenses with 3.0 diopters or diffractive multifocal intraocular lenses with 2.5 diopters near addition are implanted. Methods. 41 eyes of 41 patients in whom rotational +3.0 diopters near addition IOLs were implanted and 30 eyes of 30 patients in whom diffractive +2.5 diopters near addition IOLs were implanted after cataract surgery were reviewed. Uncorrected and corrected distance visual acuity, intermediate visual acuity, near visual acuity, and patient satisfaction were evaluated 6 months later. Results. The corrected and uncorrected distance visual acuity were the same between both groups (p = 0.50 and p = 0.509, resp.). The uncorrected intermediate and corrected intermediate and near vision acuities were better in the +2.5 near vision added intraocular lens implanted group (p = 0.049, p = 0.005, and p = 0.001, resp.) and the uncorrected near vision acuity was better in the +3.0 near vision added intraocular lens implanted group (p = 0.001). The patient satisfactions of both groups were similar. Conclusion. The +2.5 diopters near addition could be a better choice in younger patients with more distance and intermediate visual requirements (driving, outdoor activities), whereas the + 3.0 diopters should be considered for patients with more near vision correction (reading).